Clinical Research of the Interlaminar Approach through a Small Incision Spinal Decompression and Local Chemotherapy in Spinal Tuberculosis

Presented at SMISS Annual Forum 2013
By Xifeng Zhang MD
With Lin Zhang , Jianfei Ji , Bo Liu , Songhua Xiao , Zhengsheng Liu , Yonggang Zhang , Baowei Liu , Shourong Zhu , Ning Lu ,

Disclosures: Xifeng Zhang MD None Lin Zhang None, Jianfei Ji None, Bo Liu None, Songhua Xiao None, Zhengsheng Liu None, Yonggang Zhang None, Baowei Liu None, Shourong Zhu None, Ning Lu None,

Objective: To assess the clinical efficiency of local chemotherapy combined with percutaneous pedicle screw in adjacent vertebra in the treatment of spine tuberculosis.

Methods: From April 2007 to June 2011, 19 advanced spinal tuberculosis patients were treated by local chemotherapy combined with percutaneous pedicle screw in adjacent vertebrae. Among them, there were 9 males and 10 females. Their ages ranged from 19 to 85 years, with an average of 61 years. There were 4 in thoracic,and 15 in lumbar. T6-7, T10-11, T11-12, T12-L1, All cases have no spinal cord injury.

Results: The follow-up of 12 to 52 months, an average of 18 months. 18 patients recovered. One patient the primary lesion abscess development, anterior debridement and fusion. Follow-up period, there was no pedicle screw and rod breakage, cutting phenomenon occurred in 2 cases, preoperative Cobb angle of 5.5 ° ~ 16.3 °, an average of 9.7 °, the last follow-up Cobb angle of 6.0 ° ~ 14.6 °, an average of 10.4 °, the two groups no significant difference in Cobb angle (P> 0.05).

Conclusion: Local chemotherapy combined with percutaneous pedicle screw in adjacent vertebrae is one of method to treat spine tuberculosis,which has some advantages including fewer traumas,less blood lose, earlier action and no kyphotic angle increase.