Kyphoplasty and Spondyloplasty Improve The Quality Of Life In Metastatic Spine Disease

Presented at SMISS Annual Forum 2014
By Charalampos Matzaroglou
With

Disclosures: Charalampos Matzaroglou None

Introduction:
Spinal metastatic disease is very common in patients with cancer. The goals of therapy are pain control and functional preservation. Kyphoplasty and spondyloplasty are minimal invasive procedures that play a crucial role in the treatment of spinal metastatic spine disease.

Aims/Objectives:
We assess the quality of life, anxiety and depression in long term follow up, after kyphoplasties and spondyloplasties in thoracic and lumbar spinal metastatic fractures and lytic lesions with EuroQuol (EQ - 5D) and HADS instruments.

Methods:
One hundred-seven patients (60 men - 47 women, mean age: 62,4 years old) underwent 141 procedures. Patient-related outcomes EuroQuol (EQ - 5D) and HADS (Hospital Anxiety and Depression Scale) instruments, were assessed pre- and post-operatively and after 3, 12, 24 months, 3 years and 4 years follow up.

Results:
Mean EQ-5D and HADS scales significantly improved (32% and 41%) from pre- to post-treatment (P < 0.0001). This improvement being sustained up to 3 years follow up. Procedures were associated with a rate of 4.24% cement leakage but with no symptomatic cement leaks or serious adverse events were seen during the 4 years of follow up.

Conclusions:
Kyphoplasty and spondyloplasty are minimally invasive procedures, are used to augment vertebral body strength and improve dramatically the quality of life, the anxiety, depression and functional ability in patients with metastatic spine disease.